ABSTRACT
Objective: To systematically review the evidence and make recommendations with regard to diagnostic
utility of cervical and ocular vestibular evoked myogenic potentials (cVEMP and oVEMP,
respectively). Four questions were asked: Does cVEMP accurately identify superior canal dehiscence
syndrome (SCDS)? Does oVEMP accurately identify SCDS? For suspected vestibular
symptoms, does cVEMP/oVEMP accurately identify vestibular dysfunction related to the saccule/utricle?
For vestibular symptoms, does cVEMP/oVEMP accurately and substantively aid
diagnosis of any specific vestibular disorder besides SCDS?
Methods: The guideline panel identified and classified relevant published studies (January 1980–
December 2016) according to the 2004 American Academy of Neurology process.
Results and Recommendations: Level C positive: Clinicians may use cVEMP stimulus threshold
values to distinguish SCDS from controls (2 Class III studies) (sensitivity 86%–91%, specificity
90%–96%). Corrected cVEMP amplitude may be used to distinguish SCDS from controls (2
Class III studies) (sensitivity 100%, specificity 93%). Clinicians may use oVEMP amplitude to
distinguish SCDS from normal controls (3 Class III studies) (sensitivity 77%–100%, specificity
98%–100%). oVEMP threshold may be used to aid in distinguishing SCDS from controls (3 Class
III studies) (sensitivity 70%–100%, specificity 77%–100%). Level U: Evidence is insufficient to
determine whether cVEMP and oVEMP can accurately identify vestibular function specifically
related to the saccule/utricle, or whether cVEMP or oVEMP is useful in diagnosing vestibular
neuritis or Ménière disease. Level C negative: It has not been demonstrated that cVEMP substantively
aids in diagnosing benign paroxysmal positional vertigo, or that cVEMP or oVEMP aids
in diagnosing/managing vestibular migraine
Neurology 2017
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