Dementia in 2013: Frontotemporal lobar degeneration—building on breakthroughs

Genetic research in frontotemporal lobar degeneration (FTLD) is gaining momentum. Following the discovery of a repeat expansion in the gene C9 open reading frame 72 (C9orf72), three major genes and associated disease mechanisms and inclusion body pathologies have emerged, paving the way for personalized medicine in FTLD.

Nature Reviews Neurology 2014